henderson-dating review
Antidepressant utilisation and you will frequency from weight gain throughout the a decade’ follow-up: populace situated cohort data
Fundamental lead tips The main effects was basically antidepressant prescribing, incidence off ?5% upsurge in lbs, and you can transition so you can obese or carrying excess fat. Adjusted price rates was indeed projected out-of a Poisson design changing to possess many years, intercourse, anxiety recording, comorbidity, coprescribing away from antiepileptics or antipsychotics, starvation, smoking, and advice on diet.
Results In the year of study entry, 17 803 (13.0%) men and 35 307 (22.4%) women with a mean age of 51.5 years (SD 16.6 years) were prescribed antidepressants. During 1 836 452 person years of follow-up, the incidence of new episodes of ?5 weight gain in participants not prescribed antidepressants was 8.1 per 100 person years and in participants prescribed antidepressants was 11.2 per 100 person years (adjusted rate ratio 1.21, 95% confidence interval 1.19 to 1.22, P<0.001). (المزيد…)